Microfluidics for Biologists

This book describes novel microtechnologies and integration strategies for developing a new class of assay systems to retrieve desired health information from patients in real-time. The selection and integration of sensor components and operational parameters for developing point-of-care (POC) are also described in detail. The basics that govern the microfluidic regimen and the techniques and methods currently employed for fabricating microfluidic systems and integrating biosensors are thoroughly covered. This book also describes the application of microfluidics in the field of cell and molecular biology, single cell biology, disease diagnostics, as well as the commercially available systems that have been either introduced or have the potential of being used in research and development. This is an ideal book for aiding biologists in understanding the fundamentals and applications of microfluidics.

This book also: Describes the preparatory methods for developing 3-dimensional microfluidic structures and their use for Lab-on-a-Chip design Explains the significance of miniaturization and integration of sensing components to develop wearable sensors for point-of-care (POC)

Demonstrates the application of microfluidics to life sciences and analytical chemistry, including disease diagnostics and separations

Motivates new ideas related to novel platforms, valving technology, miniaturized transduction methods, and device integration to develop next generation sequencing

Discusses future prospects and challenges of the field of microfluidics in the areas of life sciences in general and diagnostics in particular

Describes the preparatory methods for developing 3-dimensional microfluidic structures and their use for Lab-on-a-Chip design Explains the significance of miniaturization and integration of sensing components to develop wearable sensors for point-of-care (POC) Demonstrates the application of microfluidics to life sciences and analytical chemistry, including disease diagnostics and separations Motivates new ideas related to novel platforms, valving technology, miniaturized transduction methods, and device integration to develop next generation sequencing Discusses future prospects and challenges of the field of microfluidics in the areas of life sciences in general and diagnostics in particular Includes supplementary material: sn.pub/extras

Autorentext
Chandra Dixit is in the Department of Chemistry at the University of Connecticut.

Ajeet Kaushik is in the Department of Immunology at Florida International University.
Gerson Aguirre is in the Biomedical Engineering Department at McGill University.

Inhalt
Preface.- 1. Fundamentals of Fluidics.- 2. Microfluidics Overview.- 3. Manufacturing Methods Overview for Rapid Prototyping.- 4. 3D Printed Microfluidic Devices.- 5. The Centrifugal Microfluidic: Lab-on-a-Disc Platform.- 6. Materials and Surfaces in Microfluidic Biosensors.- 7. Paper Microfluidics.- 8. Biological Applications of Microfluidics System.- 9. On-chip Immunoassay for Molecular Analysis.- 10. Challenges and Future.