MicroRNAs and Other Non-Coding RNAs in Inflammation

The book serves as a comprehensive resource for scientists and clinicians studying the role of non-coding RNAs in inflammation (viral infections, wound inflammation), human inflammatory diseases (i.e. rheumatoid arthritis, Crohn's disease, diabetes) and innate immunity. It provides a universal reference work comprising both basic and specialized information. Given that ncRNAs represent new therapeutic targets, this volume will also be of interest to industrial biomedical researchers and those involved in drug development.

Comprehensive overview of the role of miRNAs and other ncRNAs in innate immunity and inflammation Chapters highlight recent advances in specific topics, like ncRNAs in human inflammatory diseases (RA, obesity, cancer, diabetes etc.) Resource for scientists and clinicians, providing both basic and specialized information

Inhalt

The biology of microRNA.- The biology of long non-coding RNA.- microRNA regulation of neutrophil function.- How non-coding RNAs contribute to macrophage polarization.- Endogenous control of dendritic cell activation by miRNA.- Noncoding RNA expression during viral infection: the long and the short of it.- Wound inflammation: emerging role of miRNA.- The importance of microRNAs in rheumatoid arthritis.- MicroRNAs with impact on adipose tissue inflammation in obesity.- The relationship between miR-29, NOD2 and Crohn's disease.- The role of ncRNA in diabetes.- ncRNA as diagnostics and prognostics for hepatocellular carcinoma.