Molecular Aspects of Neurodegeneration, Neuroprotection, and Regeneration in Neurological Disorders

Molecular Aspects of Neurodegeneration, Neuroprotection, and Regeneration in Neurological Disorders presents readers with comprehensive and cutting-edge information on the neurochemical mechanisms of various types of neurological disorders. The book covers information on signal transduction processes associated with neurochemistry of neurological disorders, including neurodegenerative, neurotraumatic, and neuropsychiatric disorders. The book also discusses risk factors, symptoms, pathogenesis, biomarkers, and the potential treatments of neurological disorders. The comprehensive information in this monograph may not only help in early detection of various neurological disorders, but will also promote the discovery of new drugs.

Autorentext

Akhlaq A. Farooqui is a leader in the field of signal transduction processes, lipid mediators, phospholipases, glutamate neurotoxicity, and neurological disorders. He is a research scientist in the Department of Molecular and Cellular Biochemistry at The Ohio State University. He has published cutting edge research on the role of phospholipases A2 in signal transduction processes, generation and identification of lipid mediators during neurodegeneration by lipidomics. He has studied the involvement of glycerophospholipid, sphingolipid-, and cholesterol-derived lipid mediators in kainic acid neurotoxicity, an experimental model of neurodegenerative diseases. Akhlaq A. Farooqui has discovered the stimulation of plasmalogen- selective phospholipase A2 in brains of patients with Alzheimer disease (AD). Stimulation of this enzyme may not only be responsible for the deficiency of plasmalogens in neural membranes of AD patients, but also be related to the loss of synapse in the AD.

Inhalt

1. Molecular aspects of neurodegeneration and classification of neurological disorders2. Effect of diet on neurological disorders and regenerative processes in the brain3. Molecular mechanisms of neurodegeneration in neurotraumatic diseases4. Molecular mechanisms of neurodegeneration in neurodegenerative diseases 5. Molecular mechanisms of neurodegeneration in neuropsychiatric diseases6. Molecular aspects of regeneration and neuroprotection in neurotraumatic diseases7. Molecular aspects of regeneration and neuroprotection in neurodegenerative diseases 8. Molecular aspects of regeneration and neuroprotection in neuropsychiatric diseases9. Strategies for the potential treatment of neurological disorders with Chinese and Indian medicinal plants10. Summary, perspective, and future studies on neurodegeneration and regeneration in neurological disorders