Molecular Basis of Health and Disease

This book examines how the balance between pro- and anti-inflammatory molecules is related to health and disease. It suggests that this balance, or lack of it, initiates and aggravates many diseases and analyzes both them and new methods in their management.

Perinatal origins of adult diseases Adult diseases as low-grade systemic inflammatory conditions Inflammation as the basis of obesity, insulin resistance, metabolic syndrome and cancer Imbalance in the pro- and anti-inflammatory molecules as the basis of adult diseases Altered metabolism of essential fatty acids and eicosanoids in the pathobiology of adult diseases Includes supplementary material: sn.pub/extras

Inhalt

About the Author.- Preface.- Dedication.- Chapter 1: Introduction.- Chapter 2: Health and Disease as two sides of the same coin.- Chapter 3: Inflammation.- Chapter 4: Essential fatty acids-Biochemistry, Physiology and Clinical Significance.- Chapter 5: Cell membrane organization.- Chapter 6: Low-grade systemic inflammation is common in iseases/disorders.- Chapter 7: Obesity.- Chapter 8: Hypertension.- Chapter 9: Insulin resistance, dyslipidemia, type 2 diabetes Mellitus and metabolic syndrome.- Chapter 10: Atherosclerosis.- Chapter 11: Osteoporosis.- Chapter 12: Alzheimer's disease, schizophrenia and depression.- Chapter 13: Rheumatological conditions.- Chapter 14: Cancer.- Chapter 15: Aging.- Chapter 16: Adult diseases and low-grade systemic inflammation have their origins in the perinatal period.- Chapter 17: Clinical implications.