Molecular Biology of Steroid and Nuclear Hormone Receptors

Klappentext

1. The Role of Heat Shock Proteins in the Regulation of Steroid Receptor Function.- 2. Subcellular and Subnuclear Trafficking of Steroid Receptors.- 3. Structure and Function of the Steroid and Nuclear Receptor Ligand-Binding Domain.- 4. Structure and Function of the Steroid and Nuclear Receptor DNA Binding Domain.- 5. Modulation of Steroid/Nuclear Receptor Dimerization and DNA Binding by Ligands.- 6. Molecular Mechanisms of Nuclear-Receptor-Mediated Transcriptional Activation and Basal Repression.- 7. Transcriptional Cross-Talk by Steroid Hormone Receptors.- 8. Chromatin and Steroid-Receptor-Mediated Transcription.- 9. Regulation of Glucocorticoid and Estrogen Receptor Activity by Phosphorylation.- 10. Monomeric Nuclear Receptors.- 11. Orphan Nuclear Receptors and Their Ligands.

   Inhalt

   The role of heat shock proteins in the regulation of steroid nuclear receptor function, Didier Picard; regulation of nuclear localization of steroid and nuclear receptors, Donald B. DeFranco; Structure and function of the steroid and nuclear receptor ligand-binding domain, S. Stoney Simmons, Jr. Structure and function of the steroid and nuclear receptor DNA-binding domain, Fraydoon Rastinejad; Modulation of nuclear receptors dimerization - cross-talk with RXR, Boris Cheskis, Leonard Freedman; Molecular mechanisms of nuclear receptor-mediated transcriptional activation and basal repression, Milan Bagchi; Receptor-mediated repression of activated transcription, Peter Herrlich, Martin Gottlicher; Chromatin and receptor-mediated transcription, Catherine E. Watson, Trevor Archer; Regulation of receptor activity by phosphorylation, Michael Garabedian et al; Mononumeric nuclear receptors, Mitchell A. Lazar, Heather P. Hardling; Orphan receptors and ligands, Barry Marc Forman.