Molecular pathological biology of Coronavirus infection SARS-CoV-2

Coronaviruses are a family of RNA viruses that infect humans and other mammals, birds and amphibians. The virus genome is single-stranded positive RNA, which codes nucleoprotein, membrane protein, envelop protein, spike glycoprotein, polymerase. Coronaviruses are characterized by glycoprotein S, the transmembrane proteins M and E, and nucleoprotein combines with the viral RNA to form a viral ribonucleoprotein complex. Severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2) membrane protein is a glycosylated structural protein that localizes to the endoplasmic reticulum and Golgi and is essential for the assembly of viral particles.

Autorentext

Dr. med. Ilie Vasiliev FWAMS, Akademieprofessor für Medizin, Erster Vizepräsident der Weltakademie der Medizinischen Wissenschaften, Vorsitzender des Allgemeinen Rates der Weltakademie der Medizinischen Wissenschaften (World Medical Council), Vorsitzender des WAMS-Nationalrates von Moldawien, Mitglied des Internationalen Wissenschaftlichen Rates der WAMS.