Multifocal role of phytoconstituents as antidepressants

Depression is a heterogeneous mood disorder that has been classified and treated in a variety of ways. Despite the fact that a variety of synthetic medications are utilized as conventional treatment for clinically depressed patients, these drugs have side effects that can jeopardize the therapeutic outcome. In recent decades, there has been a rise in research and interest in the psychopharmacology of natural treatments. Thus, it's worthwhile researching for antidepressants derived from plants that have a demonstrated effect and a favorable benefit-to-risk ratio. By virtue of their medicinal constituents, a variety of medicinal plants and medicines produced from these plants have exhibited antidepressant properties. As a result, major pharmaceutical companies are currently researching plant materials extensively for their possible medical benefit. Depression is caused by low levels of monoamines such as noradrenaline, dopamine, and serotonin in the brain. The current review focuses on medicinal plants and plant-based formulations that have been shown to have antidepressant effect in both animal and human studies.

Autorentext

Recebi o doutoramento da Universidade de Andhra no ano de 2021. O meu trabalho foi seleccionado como Melhor Tese de Doutoramento e obtive a medalha de ouro do Sri J. J. RAO. Recebeu o prémio de Melhor Investigador da INSO 2022. Tenho 12 anos de experiência de ensino e investigação. Publiquei 35 trabalhos em várias revistas nacionais e internacionais. Bolseiro da UGC.