NADH

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High Quality Content by WIKIPEDIA articles! Nicotinamide adenine dinucleotide, abbreviated NAD+, is a coenzyme found in all living cells. The compound is a dinucleotide, since it consists of two nucleotides joined through their phosphate groups, with one nucleotide containing an adenine base and the other containing nicotinamide. In metabolism, NAD+ is involved in redox reactions, carrying electrons from one reaction to another. The coenzyme is therefore found in two forms in cells: NAD+ is an oxidizing agent it accepts electrons from other molecules and becomes reduced. This reaction forms NADH, which can then be used as a reducing agent to donate electrons. These electron transfer reactions are the main function of NAD+. However, it is also used in other cellular processes, notably as a substrate of enzymes that add or remove chemical groups from proteins, in posttranslational modifications. Because of the importance of these functions, the enzymes involved in NAD+ metabolism are targets for drug discovery.

Weitere Informationen

  • Allgemeine Informationen
    • GTIN 09786130490324
    • Editor Lambert M. Surhone, Miriam T. Timpledon, Susan F. Marseken
    • EAN 9786130490324
    • Format Fachbuch
    • Titel NADH
    • Herausgeber Betascript Publishing
    • Anzahl Seiten 136
    • Genre Biologie

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