Natural Products as Enzyme Inhibitors

This book provides an overview of the latest developments and future challenges in enzyme inhibitor research. It discusses the general enzyme inhibitory principles and mechanisms in enzyme activity regulation and application of enzyme inhibitors in different areas and sectors. The major areas of applications of enzyme inhibitors covered in this book are human health management, agriculture, food processing and research, which leads to drug discovery or enzyme activity mechanisms. The book also identifies the gaps in the existing knowledge and opens up new research ideas in this important area. Currently, most enzyme inhibitors are reported to inhibit various classes of enzymes. These enzyme inhibitors are the focus of the scientific community because they may answer an increasing array of questions in the research area of biological sciences, including biochemistry, medicine, physiology, pharmacy, agriculture, ecology etc. It also serves as a useful tool inthe study of enzyme structures and reaction mechanisms and in the development of technologies in agriculture, food processing, and health management. Chapters in this book cover topics such as plant-derived inhibitors of serine proteases, pancreatic lipase (PL) inhibitors from indigenous medicinal plants, amylase inhibitors and their applications in agriculture and food processing industries and advances in silico techniques used in the study of enzyme inhibitors. The book will serve as a valuable resource for students and researchers in Life Sciences, agriculture, medicine, food processing, and allied industries.

Overviews the latest research on naturally occurring enzyme inhibitors and their applications in various fields Explains the usefulness of enzyme inhibitors in human health and in agriculture industry Explains the commercial benefits of naturally occurring enzyme inhibitors in sustainable agriculture

Autorentext

Dr. Vijay L. Maheshwari is currently working as Senior Professor & Head, Dept of Biochemistry of School of Life Sciences at Kavayitri Bahinabai Chaudhari North Maharashtra University, Jalgaon. MS, India. He has teaching experience of over 28 years. His areas of research/expertise include protein biochemistry and secondary metabolites & their biological activities. Prof. Maheshwari has received "Young Scientist" award by IUBMB, India in 1994. He is also a recipient of the BOYSCAST fellowship of Govt. of India, Dept. of Science & Technology for post-doctoral research at the University of Virginia, USA. He was Norman E. Borlaug fellow of US Department of Agriculture, USA and undertook advanced training in Risk Assessment in Genetically Modified Food. He has published around one hundred research papers and review articles in the journals of national and international repute. He has authored three books and successfully handled several research projects and supervised 22 students for doctoral degree. He has also served as editor for the book published by Springer Nature Singapore Pvt. Ltd., Singapore. Dr. Ravindra H. Patil is working as Professor in the Department of Microbiology and Biotechnology at R. C. Patel Arts, Commerce and Science College, Shirpur, MS, India. His areas of research are in microbial and plant secondary metabolites and endophyte derived natural products. He has over seventeen years of teaching experience in microbiology and biotechnology for graduate students. Six students have been awarded with PhD degree under his guidance and four are currently working. He has published over fifty research and review articles in national and international peer reviewed journals and authored three text books for undergraduate students. He has also served as editor for the book published by Springer Nature Singapore Pvt. Ltd., Singapore. Dr. Patil has also received Young Scientist award from Govt. of India, Dept. of Science & Technology in the form of research grant. He has successfully handled several research projects funded by various federal funding agencies.

Inhalt
Chapter 1. Plant peptides as protease inhibitors for therapeutic and agricultural applications.- Chapter 2.Plant peptides as protease inhibitors for therapeutic and agricultural applications.- Chapter 3.Bioactive - Amylase Inhibitors: Sources, Mechanism of Action, Biochemical Characterization and Applications.- Chapter 4.Recent Updates on In silico Screening of Natural Products as Potential Inhibitors of Enzymes of Biomedical and Pharmaceutical Importance.- Chapter 5.H+/K+-ATPase inhibitors from plants: A potential source for drug discovery.- Chapter 6.Use of protease inhibitors as a promising alternative for pest control.- Chapter 7. Pancreatic lipase (PL) inhibitors from medicinal plants and their potential applications in the management of obesity.- chapter 8. Bioactive peptides and polysaccharides- Setting a new trend in replacing conventional angiotensin-converting enzyme inhibitors.- Chapter 9.Natural Protease Inhibitors and their Therapeutic Potentials against SARS-CoV-2.-Chapter 10. Telomerase and its inhibitor in cancer therapeutics: Current status and future prospective.- Chapter 11.Metal nanomaterials as enzyme inhibitors and their applications in agriculture and pharmaceutical.- Chapter 12.-glucosidase inhibitors for diabetes/blood sugar regulation.