Novel Pyrazoline Derivatives Synthesis and It's Evaluation

The present work is a Bonafide and novel for the synthesis of Pyrazoline derivatives. In this view, we have made an extensive literature review on substituted Pyrazoline derivatives for their medicinal values with the help of chemical abstracts, journals, and internet surfing and reference books. The synthesis of Pyrazoline derivatives scheme was established based on the literature survey. Around 12 new Pyrazoline derivatives were synthesized, with the standard chemicals and well-established procedures. The synthesized compounds were tested for their Preliminary Tests, Physical Constants, and TLC etc. The structures of the final compounds were confirmed by IR, 1H-NMR Spectra and CHN analysis. The proposed compounds were screened for their Antimicrobial, Antifungal, Ant tubercular and Anti-inflammatory activities with the standard drugs in the well-equipped microbiology and pharmacology lab by using standard methods.

Autorentext

O Sr.Mayur S.Bhosale é professor assistente no Departamento de Química Farmacêutica no Colégio Rural de Farmácia de Pravara, Pravaranagar. Está a prosseguir o seu doutoramento na Universidade de Bhagwant, Rajasthan. Sr.Someshwar D.Mankar é Professor Assistente no Departamento de Farmácia no Colégio Rural de Farmácia de Pravara, Pravaranagar.