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Nuclear Localization Signal
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Details
Please note that the content of this book primarily consists of articles available from Wikipedia or other free sources online. A nuclear localization signal or sequence (NLS) is an amino acid sequence which acts like a ''tag'' on the exposed surface of a protein. This sequence is used to target the protein to the cell nucleus through the Nuclear Pore Complex and to direct a newly synthesized protein into the nucleus via its recognition by cytosolic nuclear transport receptors. Typically, this signal consists of one or more short sequences of positively charged lysines or arginines. Different nuclear localized proteins may share the same NLS. An NLS has the opposite function of a nuclear export signal, which targets proteins out of the nucleus.The first NLS to be discovered is the sequence PKKKRKV in SV40 Large T-antigen.
Weitere Informationen
- Allgemeine Informationen
- GTIN 09786130955380
- Editor Lambert M. Surhone, Miriam T. Timpledon, Susan F. Marseken
- Größe H220mm x B220mm
- EAN 9786130955380
- Format Fachbuch
- Titel Nuclear Localization Signal
- Herausgeber Betascript Publishing
- Anzahl Seiten 84
- Genre Biologie
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