Obesity, Leptin & Periodontitis-The uniting link

Leptin, a multifunctional adipokine and pleiotrophic hormone produced by the adipose tissue plays a significant role in pathogenesis of periodontitis. The purpose of this study is to compare the gingival crevicular fluid leptin levels in obese and non-obese individuals with and without Chronic Periodontitis and to lend greater clarity to the role of leptin as a reliable biomarker for Periodontitis. Leptin levels and the role of Leptin in the pathogenesis of periodontitis is still a matter to be addressed and debated. Therefore, this study is designed to assess the concentration of human leptin in GCF during periodontal health and disease and to find out the possible association between BMI and leptin; Further to, explore it s potential role in the initiation and progression of periodontal disease.

Autorentext

Dr.Priyanka K.Cholan is a top ranked gold medalist with a MDS degree in Periodontology & Oral implantology. She completed her undergraduation from Dr.MGR medical university and post graduation from SRM university and continued working in the same institution. She is also the author of several articles published in internationally reputed journals.