Organic Synthesis via Organometallics OSM 5

Interdisciplinarity is an important aspect of modem science. A convincing example is pro vided by organometallic chemistry, a discipline at the interface of inorganic and organic chemistry. Over the last 20 years, organometallic chemistry has served as an inexhaustible source of new methods of ever increasing value to organic synthesis both in the laboratory and in large scale industrial plants using transition metal catalysts. In order to strengthen collaboration between inorganic and organic chemists the "Vokswagen-Stiftung" started a new program "Organic Synthesis via Organometallics" in 1986. This program grew up to more than 60 projects over a period of six years. In addi tion to its main topic organic synthesis it covered mechanistic and structural aspects of organometallic chemistry. Scientists participating in the program met with other experts from academia and industry in a series of five symposia held in Hamburg (February 1986), WUrzburg (October 1988), Marburg (July 1990) and Aachen (November 1992). The fifth and final symposium took place in Heidelberg from September 26 to 28, 1996.

Klappentext

Organometallic chemistry and homogeneous catalysis with transition metal complexes are of increasing importance in organic synthesis. Methods from these areas allow the control of regio- and stereoselectivity with ever increasing efficiency. Recent progress and state of the art in the field are documented in this volume which covers the lectures delivered at the 5th symposium "Organic Synthesis via Organometallics" held in Heidelberg. A selection of 13 plenary and 10 invited lectures present a broad survey on new avenues in organic synthesis including timely topics such as polymer synthesis via organometallics, synthesis of new organometallics, mechanism of catalytic processes, asymmetric catalysis of carbon bond forming reactions and stereoselective synthesis of biologically active compounds.

Inhalt
Carbon-Rich Organoruthenium and Selective Catalytic Transformations of Alkynes.- Polymer Synthesis with Organometallic Intermediates.- Organoaluminum and Organogallium Complexes as Efficient and Selective Alkylating Agents.- Nickel Mediated Cyclobutabenzenes Syntheses.- Organometallics-Aided SO, S2 and S Transfer in the Synthesis of Small-Membered Heterocycles.- Stereoselective Reactions of Transition Metal Carbonyl Complexes.- Metal-Centered Coupling Reactions of C1-Ligands Analogous to Carbon Monoxide.- The Synthesis of Indoles by Transition Metal Catalyzed Addition of Alkynes to 1,2-Diazenes.- Polycyclic Ring Systems via Palladacycles as Reactive Intermediates.- Substrate Directed Diastereoselective Hydroformylation of Methallylic Alcohols.- Parahydrogen and in situ NMR-Spectroscopy as Mechanistic Tools in Catalysis.- Chiral Ligands and Chiral Pockets. Some Thoughts on Enantioselective Homogeneous Catalysis.- Application of High Pressure in Palladium Catalysis.- Asymmetric Reactions Catalyzed by Palladium-MOP Complexes.- New Chiral Ferrocenyl Ligands in Asymmetric Catalysis: Applications and Mechanistic Studies.- Mechanisms of the Catalyzed Mukaiyama Cross-Aldol Reaction.- New Rhodium Hydroformylation Catalysts.- Development of Transition Metal Complexes as Redox Reagents and Redox Catalysts.- Synthesis of Highly Enantioenriched Compounds via Iron Mediated Allylic Substitutions.- Syntheses of Biologically Relevant Target Molecules by Transition Metal-Induced C-C-Bond Formation.- Pd(II)-Catalyzed Carbonylation of Unsaturated Polyols and Aminopolyols.- New Organometallic Solutions to Problems in Polyene Natural and Unnatural Products Synthesis.