Orthopedic Stem Cell Surgery

This book is a concise guide that provides an easy to follow template for other physicians to develop similar stem cell based treatments within their specialty. It identifies and summarizes the current world-wide orthopedic stem cell trials. Organized into three sections, Orthopedic Stem Cell Surgery presents clinical studies that examine the procedures for setting up and implementing stem cell surgery within the specialty of orthopedics. Chapters maintain an accessible narrative while also addressing complex studies related to orthopedic stem cell surgery. A sister text to the recently published, Retinal and Optic Nerve Stem Cell Surgery, and Neurologic Stem Cell Surgery this expertly written book examines critical Institutional Review Board (IRB) approved studies.

Provides an easy to follow template for introducing stem cell surgery into a variety of specialties Follows a handful of routine repairs and includes several studies, independently run for each procedure Based on results from 11 years of treating approximately 600 patients with stem cell therapy

Autorentext

Jeffrey N. Weiss, M.D., is the former Chief of Retinal Surgery at the Joslin Diabetes Center in Boston, Faculty of Harvard Medical School, and Visiting Scientist at the Massachusetts Institute of Technology. Dr. Weiss is the author of more than 100 publications, including 20 books, holds more than 20 U.S. and foreign patents and has been a Reviewer for multiple scholarly journals. He has served as a Visiting Professor, performed surgery, and lectured both nationally and internationally. Dr. Weiss is also the founder of two companies, Ocular Research Associates Inc., and Micron Ophthalmic, Inc., which have manufactured and sold Dr. Weiss' inventions worldwide. Dr. Weiss was the first to invent the equipment and develop the technique to safely perform retinal vessel cannulation. This surgery remains the only option for patients with severe stroke in the eye. He was also the first to report the use of hyperbaric oxygen treatment tosuccessfully treat dry age-related macular degeneration and longer standing central retinal artery occlusions. Dr. Weiss performed the first retinal stem cell surgery in 2010, and is the Principal Investigator of The Stem Cell Ophthalmology Treatment Studies I/II, the largest retinal and optic nerve stem cell studies in the world, and The Neurologic Stem Cell Treatment Study. The studies are Institutional Review Board (IRB) approved, registered with NIH, and listed on ClinicalTrials.gov.

Klappentext

Section 1. Rotator Cuff Repair.- 1. Mesenchymal Stem Cell Augmentation in Patients Undergoing Arthroscopic Rotator Cuff Repair.- 2. Bone Marrow Derived Stem Cells for the Treatment of Rotator Cuff Tears.- 3. Regenexx SD Versus Exercise Therapy for Rotator Cuff Tears.- 4. Safety and Efficacy of Adult Adipose-Derived Stem Cell Injection Into Partial Thickness Rotator Cuff.- 5. Autologous Adult Adipose-Derived Regenerative Cell Injection Into Chronic Partial- 6. Clinical Study on Mesenchymal Stem Cells Used in the Reconstruction Surgery of the Supraspinatus.- 7. Efficacy of Microfragmented Lipoaspirate Tissue in Arthroscopic Rotator Cuff Repair.- 8. Mesenchymal Stem Cells in Rotator Cuff Repair.- 9. Treatment of Tendon Disease Using Autologous Adipose-derived Mesenchymal Stem Cells.- 10. Adipose-derived Mesenchymal Stem Cells in Osteoarthritis.- Section 2. Knee Osteoarthritis.- 11. Impact of Mesenchymal Stem Cells in Knee Osteoarthritis.- 12. Multicenter Trial of Stem Cell Therapy for Osteoarthritis (MILES) .- 13. Early Regenerative Intervention for Post-Traumatic Osteoarthritis (ERIPTO) .- 14. Prospective Evaluation of PRP and BMC Treatment to Accelerate Healing After ACL Reconstruction.- 15. Open Ended Trocar vs. Fenestrated Blunt Trocar in Bone Marrow Aspirate for Osteoarthriti.- 16. The Effect of Micro Fragmented Adipose Tissue (MFAT) on Knee Osteoarthritis.- 17. A Disease-based Treatment Study for Diagnosed Osteoarthritis Utilizing Adipose-derived Regenerative Cells.- 18. Stem Cell and Growth Factor Injury and Arthritis Clinical Research Study.- 19. Adipose-derived Mesenchymal Stem Cells in Osteoarthritis.- 20. Wharton's Jelly-derived Mesenchymal Stem Cells in Osteoarthritis.- 21. A Study Evaluating the Efficacy of a Single Injection Autologous Adipose Derived Mesenchymal Stromal Cells in Patients With Knee Osteoarthritis (ADIPOA-2) .- 22. Synovium Brushing to Augmented Microfracture for Improved Cartilage Repair (AURA).- 23. Subchondral and Intra-articular Application of Bone Marrow Concentrate for Knee Unicompartmental OA (Marrow Mule) .- 24. Treatment of Early Knee Osteoarthritis With Autologous Adipose-derived Mesenchymal Stem Cells.- 25. Clinical Study of Pulp Mesenchymal Stem Cells in the Treatment of Primary Mild to Moderate Knee Osteoarthritis.- 26. Very Small Embryonic-like Stem Cells for Knee Osteoarthritis.- 27. Allogenic Adipose Tissue-Derived Mesenchymal Progenitor Cells for the Treatment of Knee Osteoarthritis.- 28. Allogeneic Adipose Tissue-Derived Mesenchymal Stem Cells (GXCPC1) for Knee Osteoarthritis.- 29. Treatment of Knee Osteoarthritis With Autologous Adipose-derived Mesenchymal Stem Cells.- 30. Clinical Study of Umbilical Cord Mesenchymal Stem Cells (UC-MSC) for Treatment of Knee Osteoarthritis.- 31. Mesenchymal Stem Cell Transplantation for Osteoarthritis.- 32. Effectiveness of Autologous Adipose-derived Stem Cells in the Treatment of Knee Cartilage Injury.- 33.. Adipose-derived Stem Cells (ADSCs) for Knee Osteoarthritis.- 34. Allogeneic Bone Marrow MSC Therapy for Knee Osteoarthritis.- 35. Evaluate Safety and Explore Efficacy of SMUP-IA-01 in Patients With Knee Osteoarthritis.- 36. Clinical Trial to Compare ReJoinTM to Sodium Hyaluronate Injection for Knee Osteoarthritis Cartilage Defects.- 37. Follow-up Study for Participants Jointstem Clinical Trial.- 38. A Phase 3 Study to Evaluate the Efficacy and Safety of JointStem in Treatment of Osteoarthritis.- 39. Follow-up Safety and Efficacy Evaluation on Subjects Who Completed Phase I Clinical Trial.- 40. Clinical Study of Intra Articular Injection of Catholic MASTER Cell (Bone Marrow Derived Mesenchymal Stem Cell) in Knee Osteoarthritis (MSC-OA).- 41. Follow-up Study for Participants of Jointstem Phase 3 Clinical Trial.- 42. Investigator Initiated Trial to Evaluate the Efficacy and Safety of Intra-articular Injection of ADMSC Compared to Negative

Inhalt

Section 1. Rotator Cuff Repair.- 1. Mesenchymal Stem Cell Augmentation in Patients Undergoing Arthroscopic Rotator Cuff Repair.- 2. Bone Marrow Derived Stem Cells for the Treatment of Rotator Cuff Tears.- 3. Regenexx SD Versus Exercise Therapy for Rotator Cuff Tears.- 4. Safety and Efficacy of Adult Adipose-Derived Stem Cell Injection Into Partial Thickness Rotator Cuff.- 5. Autologous Adult Adipose-Derived Regenerative Cell Injection Into Chronic Partial- 6. Clinical Study on Mesenchymal Stem Cells Used in the Reconstruction Surgery of the Supraspinatus.- 7. Efficacy of Microfragmented Lipoaspirate Tissue in Arthroscopic Rotator Cuff Repair.- 8. Mesenchymal Stem Cells in Rotator Cuff Repair.- 9. Treatment of Tendon Disease Using Autologous Adipose-derived Mesenchymal Stem Cells.- 10. Adipose-derived Mesenchymal Stem Cells in Osteoarthritis.- Section 2. Knee Osteoarthritis.- 11. Impact of Mesenchymal Stem Cells in Knee Osteoarthritis.- 12. Multicenter Trial of Stem Cell Therapy for Osteoarthritis (MILES) .- 13. Early Regenerative Intervention for Post-Traumatic Osteoarthritis (ERIPTO) .- 14. Prospective Evaluation of PRP and BMC Treatment to Accelerate Healing After ACL Reconstruction.- 15. Open Ended Trocar vs. Fenestrated Blunt Trocar in Bone Marrow Aspirate for Osteoarthriti.- 16. The Effect of Micro Fragmented Adipose Tissue (MFAT) on Knee Osteoarthritis.- 17. A Disease-based Treatment Study for Diagnosed Osteoarthritis Utilizing Adipose-derived Regenerative Cells.- 18. Stem Cell and Gr…