Osteoporosis in Older Persons

This new edition includes the most up-to-date information about the pathophysiology and new therapeutic alternatives for osteoporosis of advanced age. It is written by investigators (clinicians and basic scientists) in the field of aging bone research.
It was just recently that a new syndrome, osteoporosis of advanced age, was recognized as a new entity with its own pathophysiology and potential treatments. Unfortunately, and despite the fact that hip fractures are mostly a consequence of this process, and apart from the first edition of this book, there are few publications about this subject.
The first edition of this book demonstrated that there is a need to understand the particular features of osteoporosis in older persons, which is the main aim of this book. The institutions where the authors are affiliated are highly recognized as the main centers in aging bone research. As an innovation, the second edition includes some aspects of muscle and bone interaction focusing of the impact of age-related muscle loss (sarcopenia) on the pathogenesis of falls and fractures in older persons. As in the previous edition, this book is expected to be the reference guide for geriatricians, gerontologists, and bone biologists as well as medical trainees in order to understand the mechanisms of senile osteoporosis with a practical approach to the treatment of its consequences.

This book will contain the basic biology of aging bone including the potential links between aging and the changes in bone biology This book will integrate the subject of falls with the one on fractures Figures showing the potential therapeutic targets in bone to prevent and treat osteoporosis will be complemented by a complete review on the current treatments Future treatments will be also included explaining their biological basis as well as their potential indications

Autorentext
Gustavo Duque, MD, PhD Ageing Bone Research Program Sydney Medical School Nepean The University of Sydney (Australia)
Douglas P. Kiel, MD, MPH Institute for Aging Research Hebrew SeniorLife Harvard Medical School (USA)

Klappentext

This second edition brings together the latest information about the pathophysiology and new therapeutic alternatives for osteoporosis of advanced age. Written by highly recognised clinicians and basic scientists in the field of aging bone research, this book includes aspects of muscle and bone interaction focusing on the impact of age-related muscle loss (sarcopenia) on the pathogenesis of falls and fractures in older persons.

Osteoporosis in Older Persons- Advances in Pathophysiology and Therapeutic Approach, Second Edition , aids the reader in understanding the mechanisms of senile osteoporosis with a practical approach to the treatment of its consequences. It is the perfect reference guide for geriatricians, gerontologists and bone biologists, as well as medical trainees.

Inhalt

1. Biology of Bone.- 2. Aging and Bone.- 3. Calciotropic Hormones.- 4. The Muscle-Bone Connection.- 5. Sex Steroids and Aging Bone.- 6. Animal Models for Senile Osteoporosis.- 7. Senile Osteoporosis as a Geriatric Syndrome.- 8. Genetics of Osteoporosis in Older Age.- 9. Fracture Epidemiology in Individuals 75+.- 10. Falls as a Geriatric Syndrome: Mechanisms and Risk Identification .- 11. Medical Treatment of Age Related Osteoporosis.- 12. Non Pharmacological Treatment and Prevention of Falls and Fractures.- 13. Fracture Liaison Services.- 14. Treatment of Osteoporosis in Long-Term Care.- 15. Fracture Care in the Elderly.- 16. The Orthogeriatrics Model of Care. <p