Oxidative Stress Biomarkers: Mitochondrial DNA and 8OHdG

Oxidative stress plays a key role in the development of Type 2 Diabetes. This cross-sectional study examined the relationship among serum levels of manganese superoxide dismutase (MnSOD), 8-hydroxy-2'-deoxyguanosine (8OHdG), dietary antioxidant intakes and glycemic control in African Americans and Haitian Americans with and without T2D. The results demonstrate greater oxidative mtDNA damage in persons with T2D compared to those without T2D and in African Americans compared with Haitian Americans. The inverse relationship between dietary intake of antioxidants and oxidative stress implies a potential to reduce oxidative stress with diet.

Autorentext

Michael Andrew McLean: 1986-1989 B.Sc., Biology. 1996-2002 M.Sc. - Dietetics & Nutrition. 2007-2014 Ph.D., Dietetics and Nutrition. PROFESSIONAL: 1986-2001 Laboratory Supervisor/Manager AMTL Corp. Hollywood, FL. 2001 - 2010 Lab Supervisor/Manager, Signet, Riviera Beach, FL. 2010 Present Lab Supervisor/Manager, Cell Science, Deerfield, FL.