Pathology of Malignant Mesothelioma

A known cause of malignant mesothelioma is previous exposure to asbestos fibres. The disease is of global nature. About 2,0003,000 new cases of mesothelioma are diagnosed in the US each year and this figure is increasing. Incidence is rising in Europe and there is evidence that asbestos is still being imported into developing countries By the time the symptoms appear and cancer is diagnosed, the disease is often advanced.

This book is an essential reference work for pathologists, clinicians, and specialists in the medico-legal profession having to deal with this disease.

The only up-to-date book on the market in this area (pathological diagnosis of mesothelioma)

Klappentext

Mesothelioma is a global problem. Its incidence is rising in Europe, and it is a major health problem in the USA and other parts of the world, largely related to the previous use of asbestos products. Diagnosis, which rests on the pathology, is very difficult because of its diverse appearances and the potential for other diseases to mimic it.

This monograph has been assembled by an international group of experts with a wealth of experience from France, UK, USA, Australia and Canada to aid in pathological diagnosis. In all these countries, the disease poses significant health problems. This book deals with clinical, radiological, epidemiological, molecular, and histopathological aspects of the disease. Tumors of the pleural, pericardial, peritoneal cavities as well as the ovary and tunica vaginalis are discussed. Differential diagnoses of serosal-based lesions are fully discussed and the use of immunohistochemical stains is explained. Plentiful illustrations give further aid to diagnosis

This book is an essential reading for all diagnostic pathologists as well as general pathologists, who are sometimes required to diagnose the disease at biopsy or post mortem. It will be also invaluable read for members of the medical and legal professions who are involved with various aspects of this disease.

Inhalt
Epidemiology of Mesothelioma.- Molecular Biology.- Serosal Anatomy and Anatomic Distribution of Mesothelioma.- Clinical Aspects of Mesothelioma.- Management of Malignant Serosal Effusions.- Pathologic Diagnosis and Classification of Mesothelioma.- Macroscopic Features of Mesotheliomas.- Classification and Histologic Features of Mesotheliomas.- Differential Diagnosis: Mesothelial Proliferations.- Differential Diagnosis: Other Mesothelial Lesions.- Differential Diagnosis: Nonmesothelial Lesions.- Differential Diagnosis: Nonmesothelial Tumors of the Serosal Cavity: Sarcomas.- Differential Diagnosis: Other Nonmesothelial Tumors.