Phosphatase

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Details

A phosphatase is an enzyme that removes a phosphate group from its substrate by hydrolysing phosphoric acid monoesters into a phosphate ion and a molecule with a free hydroxyl group (see dephosphorylation). This action is directly opposite to that of phosphorylases and kinases, which attach phosphate groups to their substrates by using energetic molecules like ATP. A common phosphatase in many organisms is alkaline phosphatase. Protein phosphorylation is the most common and important form of reversible protein posttranslational modification (PTM), with up to 30% of all proteins being phosphorylated at any given time. Protein kinases (PKs) are the effectors of phosphorylation and catalyse the transfer of a -phosphate from ATP to specific amino acids on proteins. Several hundred PKs exist in mammals and are classified into distinct super-families.

Weitere Informationen

  • Allgemeine Informationen
    • GTIN 09786131074332
    • Editor Lambert M. Surhone, Miriam T. Timpledon, Susan F. Marseken
    • Genre Chemie
    • Größe H7mm x B220mm x T150mm
    • EAN 9786131074332
    • Format Fachbuch
    • Titel Phosphatase
    • Gewicht 197g
    • Herausgeber Betascript Publishing
    • Anzahl Seiten 136

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