Phytochemical & Pharmacological Studies of Iris persica L.

In the first phytochemical investigation of non-volatile secondary metabolites from the Kurdish traditional plant Iris persica L, (-)-embinin was isolated from flowers and leaves, isovitexin from flowers, trans-resveratrol-3-O-beta-D-glucopyranoside from rhizomes and tectorigenin from bulbs. The complete NMR spectra of embinin are reported for the first time. In an MTT assay, embinin showed an inhibition activity higher than the well-known antitumor drug cisplatin against five of the six tested human tumor cells. Moreover, embinin showed a significant DPPH radical scavenging activity (IC50 value of 112.16) comparable to the reference antioxidant ascorbic acid. The remarkable biological activities exhibited by the extracts of Iris persica and isolated compounds have validated the uses of I. persica in the traditional medicine of Kurdistan.

Autorentext

Hawraz I. Mohammed Amin chercheur post-doc. au département de chimie/ Université de Pavie/Italie. A reçu la bourse CICOPS (CICOPS fellow) pour l'année 2018 à l'Université de Pavie/Italie. Docteur en chimie (Ph.D.) Chimie organique à l'UNIPV et à l'Université de Salahaddin. Maîtrise en chimie à l'Université de Pavie/Italie.