Porphyromonas gingivalis : Its virulence and vaccine

Porphyromonas gingivalis, a black-pigmented gram-negative anaerobic rod, has been implicated as a major pathogen of chronic periodontitis .It possesses all characteristics that make it an important member of periodontopathic microbiota - it is essentially absent in oral health & is a predominant member of the subgingival microbiota in disease and possesses and "excretes" numerous potentially toxic virulence factors. P gingivalis also produces many cell components and macromolecules that have been proposed to function as virulence factors. P.gingivalis produces a large number of hydrolytic, lipolytic and proteolytic enzymes. Major emphasis during the past several years has concentrated on the isolation and characterization of protein . Now several vaccines have also been formed to prevent against oral infections.

Autorentext

Dr. Priyanka Tikoo has done her B.D.S. & M.D.S ( Periodontics and oral implantology) from D.A.V Dental college , yamunanagar. She has a teaching experience of 2 yrs in dental college in yamunanagar. Now a private practitioner in westbengal , she is active in various camps and providing latest treatment facility to her patients .