Practical Insights into Atopic Dermatitis

This book is a comprehensive, practical guide to the latest developments in the understanding and management of atopic dermatitis. Detailed information is provided on age-specific clinical symptoms, features, and diagnostic methods. Current theories on the pathogenesis of atopic dermatitis are closely examined, with attention to the roles played by genetic, allergic, immunologic, and skin barrier dysfunctions. In the second half of the book, the scientific background to and the practical use of the full range of treatment methods are described, covering topical agents, systemic agents, phototherapy, allergen-specific immunotherapy, and the most recently developed biologics and small molecules. This textbook will be an excellent guide to diagnosis and treatment for not only dermatologists but also practitioners in allergy and general medicine, including pediatricians, allergists, and primary care physicians. In addition, it will be of value for all scientists interested in developing new drugs for atopic dermatitis.

Clear explanation of the latest theories on pathogenesis Identification of relevant environmental factors Practical guidance on diagnosis Coverage of all available treatment methods, including recently developed biologics and small molecules

Autorentext

Kwang Hoon Lee. M.D., Ph.D. Professor EmeritusDepartment of Dermatology, Yonsei University College of Medicine, Seoul, Korea Eung Ho Choi, M.D., Ph.D.Professor Department of Dermatology, Yonsei University Wonju College of Medicine, Wonju, Korea Chang Ook Park, M.D., Ph.D.Associate Professor Department of Dermatology, Yonsei University College of Medicine, Seoul, Korea

Inhalt

1. Overviews of atopic dermatitis.- 2. Clinical manifestations.- 3. Diagnosis and severity assessment.- 4. Genetics.- 5. Skin barrier related pathogenesis.- 6. Immune response related pathogenesis.- 7. Environmental factors.- 8. Food allergy.- 9. Inhalant allergy.- 10. Pruritus.- 11. Infection relation.- 12. Pychological stress.- 13. Endophenotype and Biomarkers.- 14. Topical treatment.- 15. Systemic treatment.- 16. Biologics and small molecules.- 17. Phototherapy.- 18. Allergen-specific immunotherapy.- 19. Treatment algorithms.- 20. Prevention of atopic dermatitis.