Preclinical MRI

Includes cutting-edge methods and protocols
provides step-by-step detail essential for reproducible results
Contains key notes and implementation advice from the experts

Includes cutting-edge methods and protocols provides step-by-step detail essential for reproducible results Contains key notes and implementation advice from the experts

Zusammenfassung
This book is organized into 7 parts: Part 1 covers the basics of MRI physics, relaxation, image contrast, and main acquisition sequences; Parts 5 and 6 discuss MRIs and MRSs in animal models of disease and the applications used to study them, and Part 7 looks at anesthesia and advanced contrast agents.

Inhalt
Introduction to MRI Physics.- Basic Pulse Sequences in Magnetic Resonance Imaging.- Dynamic Susceptibility Contrast MRI in Small Animals.- Preclinical Arterial Spin Labeling Measurement of Cerebral Blood Flow.- Dynamic Contrast-Enhanced MRI.- Diffusion Weighted Magnetic Resonance Imaging.- Diffusion Tensor Imaging (DTI).- Mapping Functional Connectivity in the Rodent Brain using Electric-Stimulation fMRI.- Functional Diffusion Magnetic Resonance Imaging.- In Vivo 1H Magnetic Resonance Spectroscopy.- In Vivo Heteronuclear Magnetic Resonance Spectroscopy.- 1H Spectroscopic Imaging of the Rodent Brain.- Susceptibility Weighted MRI in Rodents at 9.4T.- Biomedical 19F MRI Using Perfluorocarbons.- Rodent Abdominal Adipose Tissue Imaging by MR.- Cardiac MRI in Small Animals.- In Utero MRI in Mouse Embryos.- Oxygenation Imaging by Nuclear Magnetic Resonance Methods.- Molecular Magnetic Resonance Imaging (mMRI).- Magnetic Resonance Spectroscopy Studies of Mouse Models of Cancer.- MRI in the Study of Animal Models of Neurodegenerative Diseases.- MRI in the Study of Animal Models of Stroke.- Assessment of Blood Brain Barrier Leakage with Gadolinium Enhanced MRI.- In Vivo Pharmacokinetics of Magnetic Nanoparticles.- Anaesthesia and Monitoring of Animals during MRI Studies.- Advanced Contrast Agents for Multimodal Biomedical Imaging Based in Nanotechnology.