Progressive Multiple Sclerosis

Reflecting significant recent advances, this accessible, clinically focused book reviews the basic science, pathology, epidemiology and state-of-the-art treatment in progressive multiple sclerosis. Discussion includes emerging and future therapies and more.

Provides an update on current treatment and recent trials concerning progressive multiple sclerosis (MS)

Guides physicians who manage patients with progressive MS

Reviews current theories concerning pathophysiological mechanisms of progressive MS disease progression

Relates basic research to potential therapies in progressive MS

Autorentext

Dr Alastair Wilkins (BA, MB,BChir, PhD(Cantab)) is Reader in Neurology, University of Bristol, and Consultant Neurologist at Southmead Hospital, Bristol, UK. He researches axonal injury in multiple sclerosis and related disorders.

Inhalt

General introduction.- What is disease progression?- Clinical scales of disease progression and disability.- Primary progressive MS.- Epidemiology of progressive multiple sclerosis.- The neuropathology of progressive multiple sclerosis.- Mechanisms of disease progression.- Axonal injury.- Imaging disease progression.- Biomarkers of disease progression.- Symptomatic treatment for progressive multiple sclerosis.- Trials of licenced RRMS disease modifying therapies in progressive MS.- Trials of novel therapies specifically for progressive MS.- Rehabilitation.- Future therapies for progressive multiple sclerosis.