Proopiomelanocortin
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Details
Please note that the content of this book primarily consists of articles available from Wikipedia or other free sources online. Pro-opiomelanocortin (POMC) is a precursor polypeptide with 241 amino acid residues. This gene encodes a polypeptide hormone precursor that undergoes extensive, tissue-specific, post-translational processing via cleavage by subtilisin-like enzymes known as prohormone convertases. There are eight potential cleavage sites within the polypeptide precursor and, depending on tissue type and the available convertases, processing may yield as many as ten biologically active peptides involved in diverse cellular functions. The encoded protein is synthesized mainly in corticotroph cells of the anterior pituitary where four cleavage sites are used; adrenocorticotrophin, essential for normal steroidogenesis and the maintenance of normal adrenal weight, and lipotropin beta are the major end products.
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GarantieWeitere Informationen
- Allgemeine Informationen
- GTIN 09786130975715
- Editor Lambert M. Surhone, Miriam T. Timpledon, Susan F. Marseken
- Genre Chemie
- Größe H220mm x B220mm
- EAN 9786130975715
- Format Fachbuch
- Titel Proopiomelanocortin
- Herausgeber Betascript Publishing
- Anzahl Seiten 88
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