Protein Targeting, Transport, and Translocation

This book presents an in-depth overview on the topic of protein synthesis, covering all areas of protein science, including protein targeting, secretion, folding, assembly, structure, localization, quality control, degradation, and antigen presentation. Chapters also include sections on the history of the field as well as summary panels for quick reference. Numerous color illustrations complement the presentation of material. This book is an essential reference for anyone in biochemistry and protein science, as well as an excellent textbook for advanced students in these and related fields.

Key Features

• Basic principles and techniques
• Targeting adn sorting sequences
• Protein export in bacteria
• Membrane protein integration into ER and bacterial membranes
• Protein translocation across the ER
• Disulfide bond formation in prokaryotes and eukaryotes
• Quality control in the export pathway
• Import of proteins into organelles
• The secretory pathway
• Vesicular transport

• Spectacular color throughout

  Zusammenfassung
  Presents an in-depth overview on the topic of protein synthesis and covers various areas of protein science, including protein targeting, secretion, folding, assembly, structure, localization, quality control, degradation, and antigen presentation. This book also includes sections on the history of the field and summary panels for quick reference.

  Inhalt

  Methods in Protein Targeting, Translocation and Transport
  Targeting Sequences
  Protein Export in Bacteria
  Protein Sorting at the Membrane of the Endoplasmic Reticulum
  Membrane Protein Insertion into Bacteial Membranes and Endoplasmic Reticulum
  Disulfide Bond Formation in Prokaryotes and Eukaryotes
  The Unfolded Protein Response
  Protein Quality Control in the Export Pathway: The Endoplasmic Reticulum and its Cytoplasmic Proteasome Connection
  Translocation of Proteins into Mitochondria
  The Import and Sorting of Protein into Chloroplasts
  Import of Proteins into Peroxisomes
  Nucleocytoplasmic Transport
  Protein Transport to the Yeast Vacuole
  The Secretory Pathway
  Vesicular Transport
  Conclusion/Perspective