Quinolin-3yl-chalcones and Derivatives

The content of this book describes that the efficient synthesis of 6-chloro-2-methyl-4-phenylquinolin-3-yl)-3-aryl-prop-2-en-1-ones (Chalcones) from 6-chloro-2-methyl-4-phenylquinoline and their efficient conversion into pyrazoline derivatives. Since the quinoline, chalcone pharmacophore and pyrazoline moiety are having biological importance. If they have been associated together as a single molecule the respective individual biological activity may be pronounced with this idea the synthesis of some new quinoline derivatives have been proposed, synthesized and characterized using spectral and single crystal X-ray diffraction studies and presented,further they will be explored for their activities.

Autorentext

Prof S.Sarveswari and her research group interested in the synthesis and exploring the medicinal and physical properties of 4-phenyl quinoline and other derivatives of quinoline.The author is also interseted in the exploration of medicinal properties of quinoline and quinolone derivatives