Regenerative Medicine - from Protocol to Patient

Regenerative medicine is the main field of groundbreaking medical development and therapy using knowledge from developmental and stem cell biology as well as advanced molecular and cellular techniques. This collection of volumes on Regenerative Medicine: From Protocol to Patient, aims to explain the scientific knowledge and emerging technology as well as the clinical application in different organ systems and diseases. International leading experts from all over the world describe the latest scientific and clinical knowledge of the field of regenerative medicine. The process of translating science of laboratory protocols into therapies is explained in sections on regulatory, ethical and industrial issues. This collection is organized into five volumes: (1) Biology of Tissue Regeneration, (2) Stem Cell Science and Technology, (3) Tissue Engineering, Biomaterials and Nanotechnology, (4) Regenerative Therapies I, and (5) Regenerative Therapies II. The textbook gives the student, the researcher, the health care professional, the physician and the patient a complete survey on the current scientific basis, therapeutical protocols, clinical translation and practiced therapies in regenerative medicine.
Volume 5 contains clinical science and translation surveys on the circulatory system, visceral, musculoskeletal and skin. The state-of-the-art descriptions involve concepts for clinical diagnosis, stem cell and gene therapy, biomaterials for tissue replacement and pharmacological/biomolecule treatment strategies.

Basic molecular mechanisms of human stem cell differentiation Molecular mechanisms and technologies for (re-)programming Analytical methods to classify stem cell fate and function Specific features of different human stem cell types Physiology and pathology of stem cells

Autorentext
Gustav Steinhoff initiated and leads the Reference and Translation Center for Cardiac Stem Cell Therapy (RTC) of the University Medical Center Rostock. He is known as an expert in the medical field of stem cell therapies and the first clinician to treat patients with intramyocardial transplantation of purified stem cells and is one of the pioneers of these new therapies. Besides his medical study at the Erasmus University Rotterdam, Gustav Steinhoff performed research at the Baylor College in Houston, Texas. He has worked as a surgeon at the University of Kiel and the Medical School Hannover, where he was appointed as an Associate Professor of Cardiothoracic Surgery in 1998. In 2000 he moved to the University of Rostock as a Director and Chairman of the Department of Cardiac Surgery where he continued his research on cardiac stem cell therapies and tissue engineering.

Inhalt
1 Blood, Michael Schmitt, Lei Wang and Mathias Freund.- 2 Vascular, Masaaki Ii, Atsuhiko Kawamoto, and Takayuki Asahara.- 3 Heart, Julia Nesteruk, Hendrikus J. Duckers, Bodo E. Strauer, Gustav Steinhoff.- 4 Emerging Concepts in Myocardial Pharmacoregeneration, Laura C. Zelarayán, Maria Patapia Zafiriou, and Wolfram Zimmermann.- 5 Liver, Amar Deep Sharma, Razvan Iacob, Tobias Cantz, Michael P. Manns, and Michael Ott.- 6 Gastrointestinal tract and Endocrine system, Carsten Keil, Elmar Jäckel, Michael P. Manns and Oliver Bachmann.- 7 Kidney, Sajoscha Sorrentino and Hermann Haller.- 8 Urogenital tract, Bastian Amend and Arnulf Stenzl.- 9 Bone, Johannes C. Reichert, A. Berner, Siamak Saifzadeh, and Dietmar W. Hutmacher.- 10 Articular Cartilage Regeneration, Georg N. Duda, Michael Sittinger, Joshua O. Eniwumide and Evi Lippens.- 11 Muscle and ligament, Thomas Mittlmeier and Ioannis Stratos.- 12 Skin, Hans G. Machens, Christina Irene Günter, Augustinus Bader.- Index.