Review: Synthesis and Biological Importance of Benzofuran Derivatives

Benzofurans and their derivatives are present in remarkable amounts in plants, although their presence has also been detected in microorganisms and animal sources. It was synthesized from variety of substituted phenols, iodophenols, o-hydroxybenzaldehydes, o-hydroxyacetophenone, etc and study their biological activity. It was one of the most biological potent skeleton. Several studies have revealed that various substituents on the benzofuran core structure influence different biological activities such as anti-tumor, anti-coagulant, anti-inflammatory, anti-oxidant, anti-HIV and anti-bacterial.

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Dr. Bapu R Thorat Ph.D. in chemistry published more than 88 research papers, and 18 books, has 2 patents in his credits.Dr. Rupali Manikrao Biradar - Ph.D. in Botany has 15 years of research experience. Expert in chromatography and applied science.Megha Rai has published 72 research papers and completed one major research project at UGC.