Serotonin

This volume represents the proceedings ofthe invited lectures ofthe first International Symposium on "Serotonin from Cell Biology to Pharmacology and Therapeutics" which was held in Florence on March 29 -Aprill, 1989. This meeting, held under the co-sponsorship of the Serotonin Club and the Fondazione Giovanni Lorenzini, represents the first attempt to bring together scientists fascinated by the complexity of the action of 5-hydroxytryptamine throughout the body and in various species. Hence this volume provides the reader with the unique overview of the sources, effects, receptors, physiological actions and pathological role of Serotonin. As such it will be of interest not only to the person devoting herorhis research efforts to the study of 5-hydroxytryptamine but also to all scholars and even clinicians wanting to know how the powerful monoamine can modulate cellular functions. To accelerate the publication of these proceedings the Editors and the publishers have selected the camera ready format and have avoided a lengthy refereeing process. Hence the scientific content of, and the opinions expressed in the chapters are the sole responsibility of the authors. The Editors Milan and Houston The Editors want to thank Mrs. H. Liepman and her staff at Kluwer for the prompt and efficient handling of the manuscripts.

Klappentext

This volume represents the proceedings of the invited lectures of the second International Symposium on Serotonin from Cell Biology to Pharmacology and Therapeutics, which was held in Houston, September 1992, under the co-sponsorship of the Serotonin Club, Baylor College of Medicine, the Giovanni Lorenzini Medical Foundation (Houston), and the Fondazione Giovanni Lorenzini (Milan). The symposium brought together pharmacologists, physiologists, molecular biologists, and clinical scientists working in the complex field of serotonin. Hence this volume provides the reader with a unique overview of the sources, effects, receptors, molecular biology, physiological actions and pathological roles of serotonin agonists and antagonists. As such the book will be of interest both to persons devoting their research efforts to serotonin as well as to all scholars and clinicians wanting to know how this powerful monoamine can modulate cellular functions.

Inhalt
Serotonin research: historical overview.- Molecular Mechanisms in Serotonin Mediated Response.- Physiology of Serotonergic System: - Vascular System.- Serotonergic Receptors: Biochemistry, Physiology and Pharmacology.- Pharmacology of Serotonergic System.- Short and Long Term Effects of Substituted Amphetamines.