Simultaneous estimation of combination tablet dosage form by HPLC

The new products which are coming up by certain pharmaceutical companies are in combination of different drugs, rather than a single drug alone. These drug combinations have a wider range to treat as compared to single drug component. Hence Quantitative analysis of multicomponent formulations usually requires a prior separation of drugs from the excipients or elaborate separation procedures for multiple drugs themselves. Regardless of the various pharmaceutical and reported methods available, development of a simple and systematic procedure that given as clear separation of drugs is a difficult endeavor. The presence of additives and decomposition products further complicates the development of analytical procedures. As a result, simple, rapid and economical methods for the simultaneous analysis of multicomponent formulation, which don't require extraction or separation of the analyte from themselves or from the excipients, becomes necessary for the pharmaceutical industry.

Autorentext

Mr. Sunil Singh, B.Pharm, M.Pharm (Pharmaceutical Chemistry) is Associate Professor in NRI Institute of Pharmaceutical Sciences Bhopal ,India.He has more than 07 years of teaching experience.He has published more than 10 Research papers in National & International journals.He has actively participate in many Conferences and Seminars.