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Single-Nucleotide Polymorphism
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High Quality Content by WIKIPEDIA articles! A single-nucleotide polymorphism (SNP, pronounced snip) is a DNA sequence variation occurring when a single nucleotide ? A, T, C, or G ? in the genome (or other shared sequence) differs between members of a species (or between paired chromosomes in an individual). For example, two sequenced DNA fragments from different individuals, AAGCCTA to AAGCTTA, contain a difference in a single nucleotide. In this case we say that there are two alleles : C and T. Almost all common SNPs have only two alleles. Within a population, SNPs can be assigned a minor allele frequency ? the lowest allele frequency at a locus that is observed in a particular population. This is simply the lesser of the two allele frequencies for single-nucleotide polymorphisms. There are variations between human populations, so a SNP allele that is common in one geographical or ethnic group may be much rarer in another.
Weitere Informationen
- Allgemeine Informationen
- GTIN 09786130466725
- Editor Lambert M. Surhone, Miriam T. Timpledon, Susan F. Marseken
- Größe H220mm x B220mm
- EAN 9786130466725
- Format Fachbuch
- Titel Single-Nucleotide Polymorphism
- Herausgeber Betascript Publishing
- Anzahl Seiten 72
- Genre Biologie
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