Snake venom and Hemostatic mechanism

Venoms of viperid and crotalid snakes are rich sources of components that can affect haemostasis by causing changes in blood coagulation and platelet function. Venom components affecting the clotting system include thrombin-like enzymes (TLE) which convert fibrinogen to fibrin, and activators of prothrombin, factor V and factor X. Platelet function can be affected by venom components such as hemorrhagic metalloproteinases, phospholipases. As a result, it is common to find consumption of clotting factors and blood incoagulability accompanied by hemorrhage in victims of snake bite

Autorentext

Dr. Mohammed O. Rustom. Assistenzprofessor für Hämatologie an der OAU, Master of Science an der Fakultät für medizinische Laborwissenschaften der Universität Khartum, Mitglied der Internationalen Gesellschaft für Thrombose und Hämostase, Mitglied der ISLH, Leiter der Abteilung für Hämatologie und Immunhämatologie an der Fakultät für medizinische Laborwissenschaften der OAU.