SNAPSHOT AT METAL BIOLOGY

The biology of metals?; Although an apparent
oxymoron the reader is introduced to the interesting
role of metal ions in particular biological
processes, therefore blurring the conventional
limits between inorganic(dead)/organic(living)
matter. Exploring the relatively new field of
Bioinorganic Chemistry, this book contains an
initial approach towards the study of different
chemical interactions of platinum(II) and palladium
(II)ions with essential biological substrates such
as nucleobases and aminoacids, the basic components
of DNA/RNA and proteins respectively. An extension
of model systems towards more relevant cases is also
covered in this book with potential insights into
the mechanism of anti-tumoral/anti-viral metal
chemotherapeutics.
This work is of interest particularly to chemists,
biochemists, medicinal chemists and molecular
biologists.

Autorentext

Atilio I. Anzellotti, Ph.D., M.Sc., Studied Bioinorganic Chemistry at Virginia Commonwealth University (U.S.A.) and the Venezuelan Institute for Scientific Research (Venezuela). Currently is a Senior Radiochemist at IBA Molecular Inc. focused on Molecular Imaging.

Klappentext

The biology of metals?; Although an apparent oxymoron the reader is introduced to the interesting role of metal ions in particular biological processes, therefore blurring the conventional limits between inorganic(dead)/organic(living) matter. Exploring the relatively new field of Bioinorganic Chemistry, this book contains an initial approach towards the study of different chemical interactions of platinum(II) and palladium(II)ions with essential biological substrates such as nucleobases and aminoacids, the basic components of DNA/RNA and proteins respectively. An extension of model systems towards more relevant cases is also covered in this book with potential insights into the mechanism of anti-tumoral/anti-viral metal chemotherapeutics.This work is of interest particularly to chemists, biochemists, medicinal chemists and molecular biologists.