Spectral studies and biological evaluation of some metal complexes

New Mn(II), Co(II), Ni(II), Cu(II), Zn(II) and Cd(II) complexes with chelating ligand (Z)-(2-((1,3-diphenyl-1H-pyrazol-4-yl)methylene) hydrazinyl)(pyridin-2-ylamino) methanethiol were synthesized and characterized efficiently with different spectral methods. Antioxidant activity revealed that Cd(II) complex showed the highest inhibitory antioxidant activity either using ABTS method. The SOD-like activity exhibited those Cd(II) and Zn(II) complexes have strong antioxidative properties. Ni(II), Zn(II) and Cd(II) complexes were good at inhibiting the tumour cells compared to the free ligands. Ni(II) complex shows excellent activity similar to that of Fluorouracil.

Autorentext

Tarek Yousef was born in Riyadh, Saudia Arabia (1978). He has obtained his B.Sc. in General Chemistry, Mansoura University, Egypt (1999) and M.Sc. in inorganic chemistry from Faculty of science, Mansoura University, Egypt (2005). He has obtained his ph.D in inorganic chemistry from Faculty of science, Mansoura University, Egypt (2010).