Stem Cell Biology in Health and Disease

This volume examines the dual role of stem cells in health and disease. It details strategies on the use of embryonic stem cells and embryonic-like stem cells in regenerative medical purposes as well as strategies on the elimination of cancer stem cells.

Stem Cell Biology in Health and Disease presents an up-to-date overview about the dual role of stem cells in health and disease. The Editors have drawn together an international team of experts providing chapters which, in this fully-illustrated volume, discuss:

• the controversial debate on the great expectations concerning stem cell based regeneration therapies raised by the pluripotency of various stem cells.
• the advantages and concerns about embryonic stem cells (ES cells), induced pluripotent stem cells (iPS cells) and adult stem cells, such as bone marrow-derived stem cells (BMDCs).

• the type of stem cells, which has become of interest in the past decade, namely so-called cancer stem cells (CSCs). CSCs are now in the focus of cancer research since the eradication of tumour initiating cells would raise the changes of definitely cure cancer.

  Professor Dittmar and Professor Zänker have edited a must-read book for researchers and professionals working in the field of regenerative medicine and/or cancer.

  Up-to-date information on current research in stem cell biology Reflecting the two sides of stem cells Summarizes current strategies on the use of embryonic stem cells and embryonic-like stem cells in regenerative medical purposes Summarizes current strategies on the elimination of cancer stem cellls

  Autorentext
  Dr. Thomas Dittmar promovierte bei Prof. Dr. Manfred Steiner am Lehrstuhl für Finanz- und Bankwirtschaft der Universität Augsburg. Heute ist er als Associate Consultant bei der Booz, Allen & Hamilton GmbH beschäftigt.

  Klappentext

Stem Cell Biology in Health and Disease presents an up-to-date overview about the dual role of stem cells in health and disease. The Editors have drawn together an international team of experts providing chapters which, in this fully-illustrated volume, discuss:

• the controversial debate on the great expectations concerning stem cell based regeneration therapies raised by the pluripotency of various stem cells.
• the advantages and concerns about embryonic stem cells (ES cells), induced pluripotent stem cells (iPS cells) and adult stem cells, such as bone marrow-derived stem cells (BMDCs).

• the type of stem cells, which has become of interest in the past decade, namely so-called cancer stem cells (CSCs). CSCs are now in the focus of cancer research since the eradication of tumour initiating cells would raise the changes of definitely cure cancer.

  Professor Dittmar and Professor Zänker have edited a must-read book for researchers and professionals working in the field of regenerative medicine and/or cancer.

  Inhalt
  Bone marrow-derived stem cells.- Hematopoietic Stem and Progenitor Cells in Clinical Use Transplantation and Mobilization.- Ex Vivo Expansion of HSPCs.- Modulation of Hematopoietic Stem/Progenitor Cell Migration.- Properties of Mesenchymal Stem Cells to Consider for Cancer Cell Therapy.- Embryonic Stem Cells.- Alternative Embryonic Stem Cell Sources.- Cell Therapy in Parkinson's Disease.- Transplantation of Stem Cells and Their Derivatives in the Treatment of Multiple Sclerosis.- Cancer Stem Cells.- Cancer: A Stem Cell-based Disease?.- Stem Cell Niche Versus Cancer Stem Cell Niche Differences and Similarities.- The Chronically Inflamed Microenvironment and Cancer Stem Cells.- Does the Chronically Inflamed Periodontium Harbour Cancer Stem Cells?.- Leukemia Stem Cells.- Cancer Stem Cells in Solid Tumors.- One for All or All for One? The Necessity of Cancer Stem Cell Diversity in Metastasis Formation and Cancer Relapse.- Elimination of Cancer Stem Cells.- Potential Molecular Therapeutic Targets in Cancer Stem/Progenitor Cells: Are ATP-Binding Cassette Membrane Transporters Appropriate Targets to Eliminate Cancer-Initiating Cells?.