Studies in Chemistry of Oxygen & Nitrogen Heterocycles

The work of the book is devoted to a study of a series of organic reactions from readily available and less costly starting materials such as coumarins, pyrazoles, and chromones. These heterocyclic compounds were readily converted to polyketomethylene compounds by treatment with active methylene compounds such as triacetic acid lactone, dimedone, 3-methyl-1-phenyl-5-pyrazolone and nitrogenous bases such as hydrazine hydrate, phenyl-hydrazine, hydroxylamine respectively under different reaction conditions and the structures of all new compounds were identified on the basis of IR, NMR, and mass spectroscopy. Some of these synthesized compounds have been investigated for anti-inflammatory, analgesic, antipyretic and antibacterial activities. Most of the compounds have been found to possess significant activities and their effect was compared with the standard drugs.

Autorentext

Dr. Mohammad Asad completed B.SC and M.Sc from Dr. B.R. Ambedkar University Agra and doctorate from AMU Aligarh, India in 2009. He did worked as a Postdoctoral Research Fellow at University Science Malaysia in 2010-2012. His field of research is Synthetic Organic Chemistry and published his research work in various reputed Journals.