STUDIES ON PROPERTIES OF ORGANIC HYBRID HYDROGELS

Hydrogels are three-dimensional hydrophilic polymers
which swell but do not dissolve when brought into
contact with water, and they sometimes undergo a
volume phase change in response to a change in
surrounding conditions, such as temperature, pH
value, ionic strength, and electric field. In this
book, the first part, prepare a series of the
organic hybrid hydrogels based on N-
isopropylacrylamide (NIPAAm) and gelatin, and to
investigate systematically their swelling behavior
and physical properties in deionized water at
different temperatures. In second part, the
objective in this part is to investigate the effect
of the crosslinking agent of gelatin in the organic
hybrid gels on the drug release behavior for the
drugs with different molecular size and charges. In
third part, a series of hydrogels based on gelatin
and intercalated-hydrotalcite (IHT) were prepared by
crosslinked with glutaraldehyde. The effect of
different contents of IHT in the hybrid
nanocomposite gels on the swelling behavior and
physical properties was investigated. Moreover, the
drug release behaviors of these gels were also
investigated.

Autorentext

PhD: Department of Chemical and Materials Engineering at National Central University in Taiwan. Research assistant at Department of Biochemical Science and Technology in National Taiwan University.

Klappentext

Hydrogels are three-dimensional hydrophilic polymers which swell but do not dissolve when brought into contact with water, and they sometimes undergo a volume phase change in response to a change in surrounding conditions, such as temperature, pH value, ionic strength, and electric field. In this book, the first part, prepare a series of the organic hybrid hydrogels based on N-isopropylacrylamide (NIPAAm) and gelatin, and to investigate systematically their swelling behavior and physical properties in deionized water at different temperatures. In second part, the objective in this part is to investigate the effect of the crosslinking agent of gelatin in the organic hybrid gels on the drug release behavior for the drugs with different molecular size and charges. In third part, a series of hydrogels based on gelatin and intercalated-hydrotalcite (IHT) were prepared by crosslinked with glutaraldehyde. The effect of different contents of IHT in the hybrid nanocomposite gels on the swelling behavior and physical properties was investigated. Moreover, the drug release behaviors of these gels were also investigated.