Studies Toward the Total Synthesis of (+)-Providencin

This book describes a convergent synthetic efforts toward the total synthesis of providencin, a marine natural product, which shows modest anticancer activity. This approach focus on efficient synthesis of two major fragments, which possess all the carbon atoms needed for providencin, followed by assembling them. The highlights of this approach are furanose-to-cyclobutane transformation, allenone-to-furan cycloisomerization, C-H activation, aldol reaction, and Stille-coupling.

Autorentext

Somnath earned his Ph.D. degree at Oregon State University with Professor James D. White. After graduation, he joined the University of Utah to work with Professor Jon D. Rainier as a postdoctoral research fellow. Then he joined Vanderbilt University as a Drug Discovery Scientist.