Synthesis and biological evaluation of pyrano-pyrazoles

This book contains twenty novel pyrano[2,3-c]pyrazoles (N 301-320) were synthesized. Synthesis of 6-amino-5-cyano-4-aryl-4H-pyrazolo[2,3-c]pyrans (N 301-320) were achieved by biginelli reaction have been synthesized by one pot multi-component reaction of hydrazine hydrate, ethylacetoacetate, malononitrile, substituted salicylaldehyde, and ammonium chloride in the presence of ethanol as a solvent and various catalyst. The products were characterized by FT-IR, 1H NMR, 13C NMR and mass spectral analyses. The newly synthesized compounds are subjected to antibacterial, anti-tubercular and antifungal screening. Authors expected this book to contribute to this trend and multi component reactions.

Autorentext

Mamta H. Chauhan (B.Sc., M.Sc., GSET, Ph.D.). Elle travaille comme professeur adjoint au Government Science College - Veraval (Gir-Somnath). Elle a synthétisé de nombreux nouveaux hétérocycles et étudié leurs activités antimicrobiennes. Elle a publié plus de 4 articles de recherche dans des revues internationales approuvées par l'UGC. Elle a également participé à plus de 9 conférences.