Synthesis and Reactions of Some New s-Triazole Derivatives

Various 1,2,4-triazoles found extensive investigations due to their useful application in different areas of biological activity and as industrial intermediates such as antiasthmatic, antiviral, antifungal, antimicrobial, antibacterial, insecticidal, amoebicidal, hypnotic,cytotoxic and hypotensive activities. This moiety was also found in potent agonist and antagonist receptor ligands, in HIV-1 protease inhibitors and in thrombin inhibitors. Along with these significant pharmaceutical uses, 1,2,4-triazole derivatives are effectively used in polymers, dyestuff, photographic chemicals and agricultural chemicals. In view of these findings and in continuation of our work in the same field we provide in this book, the synthesis of some new s-triazole derivatives and tested for antibacterial activity.

Autorentext

Assistant Lecturer, Chemistry Department, Faculty of Science, Sohag University,24/9/2012 up to now.Demonstrator, Chemistry Department, Faculty of Science, Sohag University,24/1/2009 to 23/9/2012.*Teaching undergraduate students in practical chemistry spanning first year to final year.