Synthesis and Studies

1--The synthesis of several new polyfunctionally substituted fused pyridines v ia reaction of benz g- 4 amino , 3cyano , 2methyl, 1H quinolino, 4, 5 dione and 4-amino,3-cyano, 2methyl,1,4-piperidino ( 2,3-b) benz- g- 1,2,3,4-tetrahydroquinoline 4,5,10 trione with different reagents is described. 2--Also a series of fused and spiro pyrazolones , Isoxazolines , pyrimidines , - lactams , and thiazolidinones incorporating 4- amino 2- methyl 5,10- dioxo- 1,5,10,11- tetrahydrobenz-g- quinoline-3- carbonitrile and 4-amino -2-methyl-5,6,11- trioxo- 1,4,4a, 5,6,11,12,12a- octahydro- 1, 12- diazanaphthacene 3- carbonitrile have been synthesized by cyclocondensation addition reaction and cyclocondensation addition reaction and cycloaddition reaction of hydrazines , hydroxylamine, urea , thiourea , monochloroacetyl chloride and mercaptoacetic acid . 3-The synthesis of several new polyfunctionally substituted fused pyrimidines via reaction of 2-amino 1,4-naphthoquinone with different reagent is described.

Autorentext

Nadia Ali Ahmed Elkanzi completed her Ph.D. in organic chemistry at Faculty of Science, Chemistry department, South valley University in Aswan. Her research interest are synthesis of several heterocyclic quinone ring system utilizing different synthetic routes.