SYNTHESIS AND TECHNOLOGY OF BIS-UREA DERIVATIVES AND THEIR APPLICATION

Ureas are used in many industries: medicine, agriculture, technology, rubber industry, organic synthesis. On their basis, various preparations were obtained for the needs of the national economy. Recent research on derivatives of ureas and bis-ureas, carried out at the present time, is prompted not only by theoretical, but also by practical needs. From this point of view, urea derivatives are of undoubted interest for substances with various biological activities. They are widely used in agriculture and have found application as herbicides, fungicides, insecticides, bactericides, dyes, growth stimulants, etc. Of particular interest is the use of these compounds in medicine as antitumor, antiviral, anti-inflammatory, antiarrhythmic, vasodilator and other drugs. Purpose of the research is development of a simple, affordable synthesis method and waste-free technology for the production of previously unknown derivatives of bis-aromatic ureas; study of their properties, as well as growth-stimulating activity; development of practical proposals for the introduction of growth stimulators in the agriculture of our republic.

Autorentext

Kholboev Yusubjon Khakimovich - Head of the Department of Medical Chemistry of ASMI, PhD, Associate Professor. Makhsumov Abdukhamid Gofurovich - Honored Inventor of the Republic of Uzbekistan, (DSc), Professor. Askarov Ibragim Rakhmanovich - Chairman of the Academy of Folk medicine of Uzbekistan, Honored Inventor of Uzbekistan, (DSc), Professor.