Synthesis of Complexes of some heterocyclic ring and sulpha drugs

The solid complexes of Fe(II), Cr(III), Co(II), Ni(II), andCu(II)) with Synthesis of five and seven membranes and sulpha drugs have been synthesized and characterized by using the spectroscopic IR,1HNMR, Mass as well as by elemental analyses C,H,N and Molar conductance the were studied. The synthesized compounds founded have a strong antimicrobial activity, were assessed to their antibacterial activity by inhibition the growth of 3 strains of Gram negative bacteria Pseudomonas auerogenosia , Escherichia coli and one strain which produce enzyme called extended spectrum Beta lactemse (ESBLs) and 2 strains of Gram positive bacteria such as Bacillus cereus and Staphylococcus aureus. Therefore the chemical compound it's an important source of new antimicrobial compounds to treat bacterial. And their complexes expected have higher biological activity than it ligand.

Autorentext

Bassam Abdul Hussein Hasan Alsafee is from Iraq and has completed his Msc in Organic Chemistry in 2011 from BAMU University, India. He is currently a lecturer at the Pharmaceutical Chemistry Department, College of pharmacy - Thi Qar University. Maitham Mohamed Abdulridha is currently lecturer at Technical Institute of Shatra.