Synthesis of heterocyclic compounds and their biological activities

Inflammatory diseases and cancer are serious health problems for mankind. Many antiinflammatory and a few anticancer drugs are available in the market. Most of the drugs used clinically have serious side effects and hence there is a development of safer antiinflammatory and more active anticancer drugs. In continuation of our work in this direction, we have synthesized a number of pyridine, pyrazine, pyrimidine, pyrimidobenzimidazole, hemin & hematoporphyrin derivatives and evaluated them for their antiinflammatory, analgesics and/or anticancer activities. A few of them are very potent towards analgesics and antiinflammarory activites and one patent was also done on Thiazoline derivatives possessing anti-inflammatory and analgesic activities and their method of preparation.

Autorentext

Dr. Shefali AroraAssociate Professor and HeadDolphin (PG) College of biomedical and natural Sciences, Dehradun, India. I did Ph.d. From IIT,Roorkee (India). I have published 13 research papers in international journal and 11 paper presented in various national and international conferences in the field of heterocyclic and natural Chemistry.