Synthesis of Nucleoside Polyphosphates and their Conjugates

Nucleoside polyphosphates and their conjugates, such as nucleoside triphosphates, nucleoside tetraphosphates, sugar nucleotides, dinucleoside pyro- and higher order polyphosphates, 2',3'-cyclic nucleoside monophosphates, and 2 -deoxynucleoside-5 -tetraphosphates in which a fluorescent label is attached to the terminal phosphate have many biological roles and have been developed into drugs. However, their synthesis remains a challenge. This book discusses several novel and efficient approaches to the synthesis of nucleoside polyphosphates and their conjugates.

Autorentext

Dr. Samy M. Mohamady Ahmed B.Sc. Pharmacy, Tanta University Egypt. M.Sc.Chemistry, Dalhousie University, Canada. Ph.D. Bioorganic Chemistry, University of Waterloo,Canada. . Dr. Mohamady is currently working as Lecturer of Pharmaceutical Chemistry at the British University in Egypt.