Synthesis of Some Novel Bioactive Fused 1,2,4-Triazole

The present book comprises three chapters:Chapter I. Introduction: A full literature survey around the subject of study.Chapter II. Experimental: This chapter Involves materials, procedure, equipment and characterization of the synthesized compounds.Chapter III. Results and discussion: This chapter describes a facile and efficient synthesis of triazolo[3,4-b]thiadiazines, triazolo[4,3-b]tetrazines and triazolyl-N-N`-triazoles from reaction of 1,2,4-triazole derivative or its Schiff's base with different hydrazonoyl chlorides. This chapter also describes a facile and efficient MCR for synthesis of 2-thiazolyl pyridines from reaction of 2-bromoacetyl pyridine with different reagents. The structures of the final products were elucidated by elemental analyses and FTIR, MS, and 1H NMR.

Autorentext

Prof. Sobhi M. Gomha has been published 167 scientific papers in the fields of synthetic organic chemistry, chemistry of hydrazonoyl halides, the chemistry of enaminones, green chemistry and bioactive heterocyclic chemistry (There are about 2500 citations of his work until March 2020 (h-index 28). He supervised 20 M.Sc. and Ph.D. graduate theses.