Synthesis & Biological Evaluation Of 1,3,4 Oxadiazole Derivatives

Oxadiazole is a five mamboed heterocyclic aromatic compound having two carbon two nitrogen & one oxygen atom & two bonds having general formula Oxadiazole is consider to be derived from furan by replacement of two methane (CH=) group by two pyridine type nitrogen (-N=) called as furadiazoles. There are four possible isomer of oxadiazole depending on the position of nitrogen atom in the ring namely 1,2 ,3-oxadiazole 1, 2, 4 & 1 ,3, 4 oxadiazole. A large number of 1,3,4 oxadiazole derivatives have been found to exhibit various biological activities such as anti -inflammatory anti microbial anticancer anticonvulsant & anti hypertensive etc.

Autorentext

Vinit Raj (magister farmacji, doktor nauk farmaceutycznych*) Wydziä Nauk Farmaceutycznych, Uniwersytet Babasaheb Bhimrao Ambedkar, Lucknow, Indie. Praveen Kumar SD College of Pharmacy and Vocational Studies. Dr Arvind Kumar (magister farmacji, doktor nauk farmaceutycznych) SD College of Pharmacy and Vocational Studies, Muzaffarnagar, UP, Indie.