Synthetic Biology and Metabolic Engineering in Plants and Microbes Part A: Metabolism in Microbes: Volume 575

Synthetic Biology and Metabolic Engineering in Plants and Microbes: Part A, the new volume in the Methods in Enzymology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field.

This volume covers research methods, synthetic biology, and metabolic engineering in plants and microbes, and includes sections on such topics as the uses of integrases in microbial engineering, biosynthesis, and engineering of tryptophan derived metabolites, regulation and discovery of fungal natural products, and elucidation and localization of plant pathways.

Autorentext
John Innes Centre, Norwich Research Park, UK

Klappentext

Synthetic Biology and Metabolic Engineering in Plants and Microbes: Part A, the new volume in the Methods in Enzymology series, **continues the legacy of this premier serial with quality chapters authored by leaders in the field.

This volume covers research methods, synthetic biology, and metabolic engineering in plants and microbes, and includes sections on such topics as the uses of integrases in microbial engineering, biosynthesis, and engineering of tryptophan derived metabolites, regulation and discovery of fungal natural products, and elucidation and localization of plant pathways.

Inhalt

1. Directing Biosynthesis: Practical Supply of Natural and Unnatural Cyanobactins
   Debosmita Sardar, Ma Diarey Tianero and Eric W. Schmidt
   
   2. Synthetic Biology Approaches to New Bisindoles
      Lona M. Alkhalaf, Yi-Ling Du and Katherine S. Ryan
   3. Enzymatic [4+2] Cycloadditions in the Biosynthesis of Spirotetramates and Spirotetronates
      Bo Pang, Guannan Zhong, Zhijun Tang and Wen Liu
   4. Application and Modification of Flavin-Dependent Halogenases
      Karl-Heinz van Pée, Daniela Milbredt, Eugenio Patallo, Veit Weichold and Maria Gajewi
   5. Engineering Flavin-Dependent Halogenases
      James T. Payne, Mary C. Andorfer and Jared C. Lewis
   6. Heterologous Expression of Fungal Secondary Metabolite Pathways in the Aspergillus Nidulans Host System
      Johannes W. A. van Dijk and Clay C. C. Wang
   7. Plug-and-Play Benzylisoquinoline Alkaloid Biosynthetic Gene Discovery in Engineered Yeast
      Jeremy S. Morris, Mehran Dastmalchi, Jing Li, Limei Chang, Xue Chen, Jillian M. Hagel and Peter J. Facchini
   8. Optimizing Metabolic Pathways for the Improved Production of Natural Products
      J. Andrew Jones and Mattheos A. G. Koffas
   9. Reconstituting Plant Secondary Metabolism in Saccharomyces Cerevisiae for Production of High-Value Benzylisoquinoline Alkaloids
      Michael E. Pyne, Lauren Narcross, Elena Fossati, Leanne Bourgeois, Euan Burton, Nicholas D. Gold and Vincent J.J. Martin
   10. Engineering Microbes to Synthesize Plant Isoprenoids
       Kang Zhou, Steven Edgar and Gregory Stephanopoulos
   11. Natural Product Biosynthesis in Escherichia Coli: Mentha Monoterpenoids
       Helen S. Toogood, Shirley Tait, Adrian Jervis, Aisling Ní Cheallaigh, Luke Humphreys, Eriko Takano, John M. Gardiner and Nigel S. Scrutton
   12. High-Efficiency Genome Editing of Streptomyces Species by an Engineered Crispr/Cas System
       Yajie Wang, Ryan E. Cobb and Huimin Zhao
   13. Rapid optimization of engineered metabolic pathways with Serine Integrase Recombinational Assembly (SIRA)
       Christine Merrick, Caroline Wardrope, Jane Paget, Sean Colloms and Susan Rosser
   14. Rewiring Riboswitches to Create New Genetic Circuits in Bacteria
       Christopher J. Robinson, Daniel Medina-Stacey, Ming-Cheng Wu, Helen A. Vincent and Jason Micklefield