The Biology of Mammalian Spermatogonia

A selection of key topics provide foundation information in mammalian spermatogonial biology

Highlights include spermatogonial stem cells, genome integrity, and therapeutic potentials
A key reference for researchers new to the field through to experienced scientists

Autorentext

Jon M. Oatley, PhD, is Associate Professor and Director for the Center for Reproductive Biology, Washington State University.

Michael D. Griswold, PhD, is Regents Professor of Molecular Biosciences, Washington State University.

Inhalt
PART 1: Spermatogenesis in Mammals.- Chapter 1: Organization of the Seminiferous Epithelium and the Cycle, and Morphometric Description of Spermatogonial Subtypes (Rodents and Primates).- PART 2: Postnatal Development of the Spermatogonial Population.- Chapter 2: Transition of Prenatal Prospermatogonia to Postnatal Spermatogonia.- Chapter 3: Setting the Stage: The First Round of Spermatogenesis.- PART 3: Spermatogonial Stem Cells.- Chapter 4: Defining the Phenotype and Function of Mammalian Spermatogonial Stem Cells.- Chapter 5: The Biology of Mammalian Spermatogonia: Regulation of Spermatogonial Stem Cell Maintenance and Self-renewal.- PART 4: Spermatogonial Differentiation.- Chapter 6: Role of Retinoic Acid Signaling in the Differentiation of Spermatogonia.- Chapter 7: Gonadotropin and Steroid Hormone Control of Spermatogonial Differentiation.- PART 5: Genome Integrity of Spermatogonia.- Chapter 8: Frequency of Human Disease Mutations and Spermatogonial Stem Cell Function.- Chapter 9: The Spermatogonial Stem Cell and the Environment.- Chapter 10: Testicular Germ Cell Tumors and Teratomas.- PART 6: Tools to Study Spermatogonial Biology.- Chapter 11: Transplantation and Culture of Spermatogonial Stem Cells.- Chapter 12: In Vitro Differentiation of Spermatogonia.- PART 7: Therapeutic Potentials and Applications of Spermatogonia.- Chapter 13: Fertility Preservation in Cancer Patients.- Chapter 14: Application of Spermatogonial Transplantation in Agricultural Animals.