The Glutamate Receptors

Glutamate receptors are critically important for normal brain function. The last decade has seen remarkable advances in our understanding of the physiological function and molecular structure of these proteins. This book provides a detailed review of the field, including a topical update to two excellent books, The Ionotropic Glutamate Receptors and The Metabotropic Glutamate Receptors. An exciting primer on glutamate receptors and their central role in neurotransmission, The Glutamate Receptors covers the extraordinary research and significant developments in the decade since the previous books were published. It also offers a snapshot of where prominent scientists expect to see research heading in the future. Both insightful and comprehensive, this book provides an invaluable reference for students and scientists on nearly every aspect of glutamate receptor structure and function.

Covers the central role glutamate receptors play in neurotransmission Condenses two previous landmark volumes, The Ionotropic Glutamate Receptors and The Metabotropic Glutamate Receptors into one easily accessible volume Covers nearly every aspect of glutamate receptor structure and function for the working researcher and student

Inhalt
AMPA Receptors.- NMDA Receptors.- Kainate Receptors.- Delta Receptors.- Ionotropic Glutamate Receptors in Synaptic Plasticity.- Structural Correlates of Ionotropic Glutamate Receptor Function.- Positive Modulators of AMPA-Type Glutamate Receptors.- Clinically Tolerated Strategies for NMDA Receptor Antagonism.- The Structures of Metabotropic Glutamate Receptors.- Group I Metabotropic Glutamate Receptors (mGlu1 and mGlu5).- Group II Metabotropic Glutamate Receptors (mGlu2 and mGlu3).- Group III Metabotropic Glutamate Receptors (mGlu4, mGlu6, mGlu7, and mGlu8).- Metabotropic Glutamate Receptor-Dependent Synaptic Plasticity.- Metabotropic Glutamate Receptor Ligands as Novel Therapeutic Agents.